Adverse effects of the interaction of two or more chemicals may be greater than that of individual chemicals. This is known as the:

The concept being described is known as the synergistic effect, which refers to a situation where the combined impact of two or more chemicals is greater than the sum of their individual effects. This can lead to more severe adverse effects than would be expected if the chemicals were acting independently. In other words, when two substances are combined, they can interact in a way that enhances their overall toxicity or harmfulness, thereby presenting a greater risk in terms of health or safety.

Understanding this concept is crucial in fields such as pharmacology and toxicology, where the interactions between different drugs or chemicals can significantly influence treatment outcomes or safety profiles. It highlights the importance of being aware of the cumulative effects that may arise from exposure to multiple agents, which can sometimes be overlooked if one only considers the effects of each agent in isolation.